IVF meaning In vitro fertilisation treats infertility or genetic problems. It is the most effective form of assisted reproductive technology and can be performed using your own eggs and your partner’s sperm. Alternatively, IVF may involve eggs and sperm from a anonymous donor.
In vitro fertilization (IVF) procedure comprises of several steps — ovulation induction, egg retrieval, sperm retrieval, fertilisation and embryo transfer. One cycle of IVF could take about four weeks, and more than one cycle may be required.
ADVANTAGES OF IVF
- In case IVF is performed to treat Infertility, you and your partner might have option to try less invasive treatment before attempting IVF . You could be treated with fertility drugs to increase production of eggs or with intrauterine insemination — where sperm are placed directly in your uterus close to the time of ovulation. ( ICSI & IUI Option)
- At times, IVF is used as a primary treatment for Infertility in women above 40.
- IVF can also be tried if you or your partner has certain health conditions such as Fallopian tube damage /blockage, Ovulation disorders , Premature ovarian failure, Endometriosis , Uterine fibroids, Previous Tubal Sterilisation or Removal , Impaired Sperm Production or Function or an Unexplained infertility.
- If you or your partner is at risk of passing on a genetic disorder to your child, IVF assisted pre-implantation genetic diagnosis can help.
Chances of having a healthy IVF baby depends on many factors such as your age, cause of infertility.
- MULTIPLE BIRTHS. IVF increases the risk of multiple births in case more than one embryo is implanted in uterus. Such pregnancy carries a higher risk of early labour and low weight birth.
- OVARIAN HYPERSTIMULATION SYNDROME. Use of injectable fertility drugs to induce ovulation can result in ovarian hyperstimulation syndrome, where the ovaries become swollen and painful. Symptoms include mild abdominal pain, bloating, nausea, vomiting and diarrhea.
- MISCARRIAGE. Though the rate of miscarriage for women who conceive using IVF with fresh embryos is similar to that of women who conceive naturally. Use of frozen embryos during IVF, may slightly increase the risk of miscarriage.
- IVF EGG- RETRIEVAL PROCEDURE COMPLICATIONS. Use of an aspirating needle to collect eggs could possibly cause bleeding, infection or damage to the bowel, bladder or a blood vessel.
- ECTOPIC PREGNANCY. 2 to 5% of women opting IVF would have an ectopic pregnancy — when fertilised egg implants outside the uterus, mostly in a fallopian tube. In this case, the fertilized egg can’t survive outside the uterus, pregnancy needs terminated.
- BIRTH DEFECTS. Age of mother is the preliminary risk factor towards development of birth defects even in IVF, though there is no age-limit defined for IVF as such. Experts opine that IVF does not increase the risk of baby with birth defects.
- OVARIAN CANCER. Few early studies suggest a possibility of a link between certain medications used in stimulating egg growth and the development of a specific type of ovarian tumour. Recent studies do not support the findings though.
IVF can be financially, physically and emotionally distressing . Partners undergoing IVF might draw support from IVF counsellors, close knit of family and friends to sail through the ups and downs of Infertility treatment.
Preparing for IVF
Beginning a cycle of IVF using your own eggs and sperm, you and your partner might require undertake various tests :
Ovarian reserve testing. Semen analysis. Infectious disease screening. Practice (mock) embryo transfer. Uterine cavity exam comprising sonohysterography Or a hysteroscopy .
Cryopreservation makes future cycles of IVF less expensive and less invasive. However, live birth rate from frozen embryos is slightly lower than the live birth rate from fresh embryos. You might donate unused frozen embryos to another issueless couple or to research facility. You could also choose to discard unused embryos.
Fertility Preservation for Cancer or Other Health Conditions If the patient is about to start cancer treatment like Radiation or Chemotherapy prone to harm fertility. For the fertility preservation, IVF may be an ideal option. Women can think of having eggs harvested from their ovaries and frozen in an unfertilised state for future use. Alternatively, eggs can be fertilised and frozen as embryos for later use.
Handling Multiple Pregnancy
In case more than one embryo is transferred to uterus, IVF can result in a multiple pregnancy —posing health risks for mother and child. Fetal reduction can be thought of use to help a woman deliver fewer babies with least health risks for a better IVF experience.
IVF, ICSI and IUI are the most common available Infertility treatment options which can be further customised to suit individual medical fitments.
ICSI means Intracytoplasmic Sperm Injection, a further refinement of the IVF technique. This line of treatment is to overcome male fertility issues, such as low sperm count or poor sperm mobility, which prevents sperm from fertilising the egg naturally. It is used for surgically-retrieved sperm, or for men whose sperm has high levels of DNA damage. Instead of sperm being mixed with the egg in the lab, the best single & healthy sperm is extracted from the sample and injected directly into the egg to fertilise it.
As the sperm is injected, it bypasses the rest stages of early fertilisation. The best quality sperm gets used.
IUI means Intrauterine Insemination that involves inserting partner or donor sperm – into uterus at the time of ovulation, hoping the egg is fertilised to impregnate. However, the outcome of IUI being a close resemblance to natural conception, need for more than one insemination attempt to achieve pregnancy might arise. Its advantage lies in the fact that this is carried out without using fertility drugs, relying on the egg you naturally ovulate that month.
India is becoming the most preferred healthcare destination globally.
The superlative medical treatment provided by the skilled doctors in world-class infrastructure at nearly one third the cost compared to Western Europe, North America and some Southeast Asian countries adds up to India’s credentials.
Professional expertise in form of skilled IVF Doctors , treatment facilities with high IVF success rate and low cost IVF treatment in India attract many infertile couples across the globe.
With available services such as artificial insemination, in vitro fertilization (IVF), gamete intra fallopian transfer (GIFT), intra cytoplasmic sperm injection (ICSI), donor egg treatment, the Indian fertility industry is at its best. Couples facing infertility issues from across the globe flock to Indian IVF centres situated in large parts of Delhi, Mumbai, Kolkata, Bangalore, Hyderabad, Chennai and Lucknow, metros.
IVF & Infertility Treatment in India is performed through cutting- edge clinical solutions, research, extraordinary patient care and infrastructure of world-class standards. IVF is a complex procedure that needs highly skilled consultants, ingenious technical staff and advanced technology working with perfect harmony, enormous dedication and team work. India offers a one stop solution for all those seeking critical procedures such as IVF.
Infertility is the inability to conceive a child. A couple may be considered infertile if, after one year of regular sexual intercourse, without contraception, the woman has not become pregnant (and there is no other reason, such as breastfeeding or postpartum amenorrhoea). Primary infertility is infertility in a couple who have never had a child. Secondary infertility is failure to conceive following a previous pregnancy. Infertility may be caused by infection in the man or woman, but often there is no obvious underlying cause. Infertility can be caused by several factors including, ovulatory problems, blocked fallopian tubes, sperm problems or many other male and female factors.
Yes, about 1 in 6 of couples experience some difficulty in achieving a pregnancy.
No, both men and women can have medicalproblems that cause difficulty in conceiving; in about a third of couples, both partners have problems.
This depends on the cause of infertility and each couple´s circumstances. The woman´s age, for example, is a very important factor.
The success of treatment needs to be seen within the context of normal fertility –under the age of 30, about 85% of women will get pregnant within a year of trying.Over the age of 40, the chance each month is about 5%.
Many treatments will simply restore the “normal” chance of pregnancy, so it is stillnecessary to try for a few months. More sophisticated treatments such as IVF have higher individual success rates but, again, this is very dependent on circumstances.
Most cases of female infertility are caused by problems with ovulation (the monthly release of an egg). Without ovulation, there are no eggs to be fertilized. Some signs that a woman is not ovulating may include irregular or absent menstrual periods.Ovulation problems are often caused by polycystic ovarian syndrome (PCOS), a hormone imbalance problem which can interfere with normal ovulation.
Primary ovarian insufficiency (POI) is another cause of ovulation problems. POI occurs when a woman´s ovaries stop working normally before she is 40. POI is not the same as early menopause, as regular periods may still be present.
Some men have reduced numbers of sperm, reduced quality, or both. In some cases, there may be complete absence of sperm. These problems are sometimes related to lifestyle habits, more general medical problems, such as diabetes, or there may be genetic factors.
Infertility can be treated with medicine, surgery, artificial insemination, or assisted reproductive technology (ART), such as in-vitro fertilization (IVF). Many times these treatments are combined.
The treatment will depend on the results of a variety of tests that can be performed to determine the cause of the problem. In many cases, all that will be needed is advice – with regard to timing, for example; sometimes, lack of ovulation can be treated with simple medication. More complicated problems, such as blocked fallopian tubes, or severe male infertility, may require more sophisticated intervention.